Journal of Clinical Case Reports

A Case of Immune Complex Mediated Acute Kidney Injury Occurring in the First Few Days of Dengue Fever

Abstract

Avasthi G, Prashant B, Rahul K and Vinay S

Dengue is an important viral illness in endemic regions, with recent yearly outbreaks in Northern India. Acute kidney injury in dengue is seen usually in presence of shock and hemolysis. Direct immune mediated acute kidney injury is uncommon in dengue and usually presents late. We describe a young male with anuria and azotemia within first few days of illness, requiring hemodialysis. His low complement levels and response to corticosteroids suggest the possibility of immune complex mediated acute kidney injury, which may relate to severity of renal injury in dengue. It is important to suspect and recognize it early.