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Journal of Dermatology and Dermatologic Diseases

ISSN: 2684-4281

Open Access

A Case of Neuro Besnier−Boeck−Schaumann Disease that Co−existed with Sjogren′s syndrome

Abstract

Zhanguo Shao*

Sarcoidosis and Sjögren's syndrome (SS) coexistence has long been overlooked because sarcoidosis is considered an exclusion criterion for SS. We described a 55-year-old woman who had been diagnosed for 16 years with coexisting neurosarcoidosis and Sjögren's syndrome. She had erythema nodosum, progressive sensory and motor impairment of the extremities, dry mouth, and dry eyes when she arrived. A symmetrical pulmonary micronodule, interstitial changes, and enlarged mediastinal lymph nodes were seen on high-resolution computed tomography (HRCT) of the chest. Magnetic resonance imaging (MRI) of the spine revealed syringomyelia and thickening of the T3-9 spinal cord. She had positive ANA and anti-SSA antibodies, as well as impaired lacrimal, salivary gland, and renal tubule function. Skin and lung nodule biopsies revealed noncaseous granuloma. A biopsy of the salivary gland revealed focal lymphocyte infiltration. Criteria for classification Based on clinical and laboratory findings, this patient met the criteria for sarcoidosis and Sjogren's syndrome. This case adds to our understanding of Sjogren's syndrome and sarcoidosis overlap and provides a reference value for clinical diagnosis.

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