Aortic angiosarcoma is a rare and aggressive form of cancer originating from the endothelial cells of the aorta. Due to its rarity and nonspecific
symptoms, it often presents diagnostic challenges and is typically diagnosed at an advanced stage. This case report discusses a unique
presentation of aortic angiosarcoma manifesting primarily as musculoskeletal metastases, emphasizing the diagnostic process, clinical features,
and therapeutic considerations. A 62-year-old male with no significant past medical history presented to the orthopedic clinic with complaints
of persistent pain and swelling in his left thigh and right shoulder. The symptoms had been progressively worsening over the past six months,
significantly impairing his daily activities. There was no history of trauma or significant weight loss, and initial clinical examination suggested a
musculoskeletal origin.
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