Michael Thomas Deans
A serendipitous observation during a student class practical with liquid nitrogen led me to propose that a variant of cubic ice crystallizingon the silica helium thermometer bulb had distorted it. Pauling argued the H-bonds in hexagonal ice retain entropy at 0K. Recent evidence for a ferroelectric transition in ‘ice XIc’ at ~72 K validates that suggestion. This paper introduces a lifetime’s research based on three axioms:
1. Proton ordered ice crystallized in liquid nitrogen undergoes a ferroelectric transitionat ~72 K releasing latent energy as ~4μ laser light, ‘ice light’, matching phosphodiester bond energy.
2. Ice crystallizing in liquid nitrogen on Earth's poles during a primordial ice age released ice light. Polarised by multiple reflectionin ice clouds and surface ice, it photo-phosphorylated nucleotidesin tropical waters, creating a ‘noodle soup’ of chiral DNA. Some formed ‘transport DNA’s, tDNAs, tRNA analogues.
3. tDNAs used an ice light powered mechanism to actively transported substrates into Oparin’s ‘coacervate’ proto-cells.
The resulting model for the origin of life makes predictions consistent with scientific research. Applying evolutionary and thermodynamicprinciples reveals life’s atomic alphabet, molecular vocabulary and metabolic grammar, predating protein synthesis evolving. It offers new perspectives on metabolism, bioenergetics, genetics, endocrinology and tissue differentiation:
• Dietary prevention of health disorders including: heart attacks, cancers, diabetes and Alzheimer’s disease.
• Energy coupling for N-fixation and power generation.
• Medical diagnosis pre-empting pharmaceutical interventions.
‘Minions’, DNA-protein complexesevolved to pack chromosomes and facilitate their replication, are bound by proton ordered H-bonds using a 63-character alphabet to store information as 18-letter words. Similar words resonate and nerve fibres act as wave guides, explaining brain function. Trace element supplements and AI modelled on ‘minions’ could improve health and create user-friendly IT. These proposals are consistent with science, philosophy and tradition.
PDFShare this article
Medicinal Chemistry received 6627 citations as per Google Scholar report
