Journal of Clinical Case Reports

A Patient Diagnosed with POEMS Syndrome with Atypical Presentation: A Case Report

Abstract

Semiz H, Geana RC, Sorostinean D, Iliescu va and Dragan A

POEMS syndrome is a paraneoplastic syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyradiculoneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease. Minor features include organomegaly, endocrinopathy, characteristic skin changes, papilledema, extravascular volume overload, and thrombocytosis.