Journal of Nanosciences: Current Research

A Review on the Application of RNA based Nanotechnology in In Vivo Computation

Abstract

Anandaram H

Computing in molecular-scale has been explored from the era of pre genomics with a limitation in Moore's law for devices based on silicon. The development of in vivo computation requires low energy consumption in molecularscale. The concept of DNA computing has rationalized the basic Boolean functions into multi-layered circuits. In the Recent year, the concept of RNA nanotechnology has emerged as an alternative approach because the RNA nanoparticles are emerging as a promising medium for a nanodevice with a platform for computing in molecularscale. In RNA computing, the varieties of small RNA sequences can work antagonistically to carry out computational logic in circuits to execute the process of in vivo computation. Though RNA computation is promising in most cases, but it is still in the infant stage and there are many challenges to collaborations between the people in RNA nanotechnology and computer science to carry out the necessary advancement in performing in vivo computation by RNA Nanotechnology.