Orellana Lucas* and Serena Cottet MarÃa Daniela
Introduction: Primary Sjogren's syndrome (pSS) is an autoimmune inflammatory disease characterized by mononuclear lymphocytic infiltration of exocrine glands (especially salivary and lacrimal) in the setting of antinuclear antibodies. These patients can also develop extraglandular manifestations within which the neurological features are frequent, especially at the peripheral level but also, less frequently, at the central nervous system (CNS).
Case presentation: We describe the case of a female patient with pSS who presented with two recurrent acute neurological events associated with CNS impairment along with radiological inflammatory lesions on MRI scans, requiring hospitalization both in 2019 and 2022.
Discussion: CNS involvement in patients with pSS shows considerable clinical variability and imposes many difficulties in its differentiation from other diseases with a similar clinical course. Knowing this entity is a crucial aspect of a correct diagnosis in order to achieve adequate treatment and reduce the risk of long-term complications and sequelae.
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