Journal of Clinical Case Reports

Allergic Reaction to Rabies Vaccine in a 4-Year-Old Girl during Post-Exposure Rabies Prophylaxis: A Case Report

Abstract

Radovan Vodopija, Boro Nogalo, Mirjana Turkalj, Andrija Miculinic*, Igor Ivic-Hofman and Ante Cvitkovic

Adverse events to vaccine or vaccine induced reactions and particularly hypersensitivity post-vaccination reactions to the rabies vaccine, are very rare. Therefore, we wanted to show a case of a four-year-old girl who developed an allergic reaction after a dog and cat bite during rabies postexposure prophylaxis. Sensitization to some component of the infectious agent of the rabies vaccine, grown on purified chick embryo cells but also on human diploid cells, has been proven. Although, allergic reactions to the rabies vaccine are extremely rare, vaccination can be done following the official WHO guide for pre-exposure and post/exposure prophylaxis in humans.