Journal of Health & Medical Informatics

An Intelligent System Based on Back Propagation Neural Network and Particle Swarm Optimization for Detection of Prostate Cancer from Benign Hyperplasia of Prostate

Abstract

Farahnaz Sadoughi,Mustafa Ghaderzadeh*,Mohsen Solimany,Rebecca Fein

Conventional clinical diagnostic methods are generally based on a single classifier. In present paper, we propose a hybrid Backpropagation neural network (BPNN) classifier based particle swarm optimization (PSO) method. In the present paper by combining the principles two algorithm, we propose a new but simple hybrid algorithm called BPNN_ PSO. Our novel algorithm optimizes BPNN with PSO and reduces computational time of the training phase of BPNN. The performance of the algorithm has been tested with prostate cancer. A total of 360 medical records collected from the patients suffering from neoplasia diseases have been used to train and test the proposed algorithm. The results show that the proposed BPNN–PSO algorithm can achieve very high diagnosis accuracy (98%) and it proving its usefulness in supporting of clinical decision process of prostate cancer. Comparing the simulated results of the above two cases, training the neural network by PSO technique gives more accurate (in terms of sum square error) and also faster (in terms of number of iterations and simulation time) results than BPNN. By using these hybrid method for building machine learning classifiers, we can significantly improve diagnostic performance with respect to the results of clinical practice