Human Genetics & Embryology

Analysis of Nutrient Metabolism Pathways and Identification of Key Candidate Genes Associated with Cadmium Stress in Buckwheat Using Multiomics Analysis

Abstract

Parrotta Zhang*

Cadmium (Cd) is a heavy metal that poses significant environmental threats and can severely affect plant growth and development. Buckwheat (Fagopyrum esculentum), a pseudocereal with notable nutritional properties, is particularly sensitive to cadmium stress. Understanding how buckwheat metabolizes nutrients and identifies key genes associated with Cd stress is crucial for developing strategies to improve its tolerance. This study employs a multiomics approach, integrating transcriptomics, proteomics, and metabolomics data to elucidate the nutrient metabolism pathways and pinpoint key candidate genes involved in cadmium stress response in buckwheat. The analysis reveals significant alterations in carbohydrate, amino acid, and secondary metabolite pathways under cadmium stress. Several key candidate genes, including those involved in metal transport, antioxidant defense, and stress signaling pathways, were identified. This comprehensive analysis provides a deeper understanding of the molecular mechanisms underpinning cadmium stress in buckwheat, offering potential targets for genetic and biotechnological interventions to enhance buckwheat's resilience to heavy metal stress.