Hyperthyroidism is a common endocrine disorder characterized by an excess of thyroid hormone production. While conventional treatment options such as antithyroid drugs, radioactive iodine therapy, and surgery are effective, they can be associated with side effects and may not address underlying dysregulation of the gut microbiota observed in hyperthyroid patients. Probiotic microbial strains have emerged as a potential adjunctive therapy for hyperthyroidism due to their ability to modulate gut microbiota composition and function. This article reviews the current understanding of neuro-hormonal dynamics in hyperthyroidism and the potential impact of probiotic microbial strains on these dynamics, focusing on findings from a murine model of hyperthyroidism. Hyperthyroidism is a condition characterized by elevated levels of thyroid hormones, primarily thyroxine and triiodothyronine, which are produced by the thyroid gland. The condition is often caused by Graves' disease, an autoimmune disorder, or by nodules on the thyroid gland that produce excess hormone. Hyperthyroidism can lead to a variety of symptoms, including weight loss, increased heart rate, tremors, and anxiety. Conventional treatments for hyperthyroidism aim to reduce thyroid hormone levels and may include antithyroid drugs, radioactive iodine therapy, or surgery. However, these treatments can be associated with side effects and may not address the underlying dysregulation of the gut microbiota observed in hyperthyroid patients.
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Reports in Thyroid Research received 2 citations as per Google Scholar report
