Arboviruses, or arthropod-borne viruses, represent a significant global public health concern due to their ability to cause widespread human infections. These viruses are primarily transmitted to humans through the bites of infected mosquitoes, making these vectors essential players in the arbovirus transmission cycle. Mosquitoes have developed an intricate immune system to combat invading pathogens, including arboviruses. Research in recent years has shed light on how the mosquito's systemic immune response plays a crucial role in the detection and control of arboviral infections. Understanding this process can provide valuable insights into developing innovative strategies for controlling arboviral diseases. This article explores the mechanisms behind how arboviruses are detected through the mosquito's systemic immune response and its implications for public health.
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