Fassikaw Kebede*, Tsehay Kebede and Birhanu Kebede
Novel coronavirus 2019 (COVID-19) is a worldwide spreading pandemic respiratory disease caused by a positive single strand (RNA) virus. The assiduous and persistent endeavored efforts for effective tackling of the COVID-19 pandemic remain futile and ineffectual. This study aims to assess COVID-19 seroprevalence and associated risk factors among symptom suspected quarantined individual in North West Ethiopia.
Methods: Institutional-based survey of COVID-19 symptoms suspected quarantined individuals from 21 Aprils- 30 December 2020. The collected data were edited and enter into EPI-DATA 3.1 version, then export to STATA/R-14 (SE) software for analysis. Bi-variables logistic regression was used for candidate variables transfer to multivariable logistic regression at P-value<0.25. Adjusted odds ratio with its 95% (CI) was used to declared statically significant variables at p-value<0.05.
Results: Of total 4233 quarantined individuals who received the SARS-CoV-2 IgG antibody test, 4230/99.78% were interviewed with a 99.82% response rate. The overall seroprevalence of COVID-19 symptom suspected quarantined individuals in North West Ethiopia was found 5.11: 95% CI (4.4--5.87). The overall knowledge and practice of prevention towards COVID-19 infection on isolated individuals were found 86.17% (95%CI: 85.1--87.2) and 62.82%; 95%CI: 60.75--63.8), respectively. The risks of developing COVID-19 infection among quarantined groups who had poor knowledge and poor practice were 1.49 (AOR=1.49 95%CI: 1.13--2.2, P< 0.027), and 2.9 (AOR=2.9; 95%CI: 2.2--3.9; P<0.01) times increased.
Conclusion: The seroprevalence of the quarantined population is high as compared with previously reported. The majority of the respondents know how to prevent themselves from the COVID-19, but changing this prevention knowledge into the practice of tackling is great hiatus.
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