Multidrug-Resistant Tuberculosis (MDR-TB) is a form of tuberculosis that is resistant to at least two of the most effective first-line anti-TB drugs: isoniazid and rifampicin. It occurs when the bacteria that cause TB develop mutations that make them resistant to these drugs. MDR-TB is a serious global health concern as it is more challenging to treat and control than drug-susceptible TB. Rapid and accurate diagnosis of MDR-TB is crucial for effective patient management, initiation of appropriate treatment, and prevention of further transmission. Over the years, various diagnostic techniques have been developed and implemented to identify MDR-TB strains. In this article, we provide a comprehensive review of the different diagnostic methods used for detecting MDR-TB, highlighting their strengths, limitations and advancements.
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Clinical Infectious Diseases: Open Access received 49 citations as per Google Scholar report
