Journal of Computer Science & Systems Biology

Bioinformatic Approach for the Identification of Hepatitis B Viral Insert in The Exon Region of Human Genome

Abstract

P. Pandarinath, M. Shashi and A. Appa Rao

Hepatitis B viral sequence was downloaded from NCBI Tax Browser and scanned against complete genome of Homo sapiens for the presence of possible viral inserts in human genome. The alignments which showed more than 25-30 residues, 90-100 % identities and localization in the exon regions were only considered. The results from the computational analysis revealed that Hepatitis B virus resulted in viral segment inserted in the exon region of human genome.