Journal of Sports Medicine & Doping Studies

Brief Exercise Enhances Blood Hypocretin-1 in Sedentary Men

Abstract

Giovanni Messina, Giovanni Di Bernardo, Antonietta Messina, Carmine Dalia, Sergio Chieffi, Umberto Galderisi and Marcellino Monda

The aim of this experiment was to test the effect of brief exercise on the concentration of plasma hypocretin-1, a peptide that regulates many physiological variables. Blood samples were collected from participants (men, n=6) before (time 0 min) and after (times 15 and 30 min) a cycle ergo meter exercise at 75 W for 15 min. The physical exertion was monitored by heart rate registration. The exercise causes a significant increase in plasmatic hypocretin-1, in association with an increase of hearth rate. These results are the first demonstration, which indicates that plasma hypocretin-1 is involved in the reactions induced by physical activity.