Biofilms are cell populations that are growing in a controlled way and displaying tolerance to harsh surroundings. Due to the recurring nature of the infections and the rise of antibiotic resistance, biofilm-related illnesses are challenging to manage. Polymicrobial or mixed species interactions, as those seen in cystic fibrosis, otitis media, dental caries, and chronic wound infections, contribute to the majority of microbial illnesses. Based on in vitro and in vivo models, as well as various therapeutic approaches for polymicrobial biofilms, this review focuses on the polymicrobial interactions among bacterial-bacterial, fungal-fungal, and bacterial-fungal aggregations. Research on anti-microbials benefits greatly from understanding the processes of polymicrobial interactions and microbial diversity in chronic illnesses. We have talked about how metagenomic methods can be used to analyse polymicrobial biofilms. the exceptional Review of advancements in polymicrobial research, particularly the use of metagenomics and model systems for the early detection, prevention, and management of infections.
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Journal of Infectious Diseases and Medicine received 59 citations as per Google Scholar report
