Journal of Cosmetology & Trichology

Common Imitators of Subcutaneous Panniculitis-like T-Cell Lymphoma

Abstract

Tatsiana Pukhalskaya

The differential diagnosis of a lobular panniculitis without vasculitis can be extensive. This review article is based on a case we recently described and is aimed to address the most common variants of lobular panniculitis that could be mistaken for Subcutaneous Panniculitis-Like T-cell Lymphoma (SPTCL). The neoplastic lymphocytes express CD8+ with rearranged an α/β subunit of the T-cell receptor. Cytotoxic markers are always expressed (TIA1, perforin, and granzyme B), but CD56 and CD30 are consistently negative