Nikita Pandit*, Yogranjan Singh, R.S. Chauhan and Chetana Deoghare
In India, for many cultures, the cow (or Kamadhenu) is a sacred animal. The current research set out to determine if cow urine concentrate made through total evaporation of cow urine retained any of its antimicrobial, antifungal, or anthelmintic properties. The disc diffusion method was utilized to examine antimicrobial activity against both Gram-positive and Gram-negative bacteria. Antifungal activity was evaluated against several Aspergillus species using the agar-well diffusion technique. An adult Indian earthworm model was used to study the anthelmintic activity. The CUC noticed a notable inhibition of Gram-positive bacteria. It was discovered that fungi inhibition was dose-dependent. Among the tested fungi, A. niger showed the greatest sensitivity. Worm mortality in the anthelmintic assay was found to be concentration dependent and CUC was found to have a more beneficial effect than the gold standard anthelmintic, piperazine citrate. The antibacterial and anthelmintic properties of CUC may be due to the presence of components. CUC can be used to treat conditions caused by opportunistic fungi, parasitic helminths and pathogenic bacteria. Isolation of inhibitory components and in vivo experiments require further study.
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