Nosha Farhadfar, Amishi Desai, Abirami Sivapiragasam, Joshua Harris, Anish Desai and Alexander Hindenburg
Post-Transfusion Purpura (PTP) is a rare, yet potentially fatal bleeding disorder characterized by severe
thrombocytopenia, purpura and hemorrhage that occurs after transfusion of blood product. It is caused by
alloimmunization against platelet antigens, anti-HPA-1a being the most frequent antibody. We report a rare case
of PTP due to an even more unusual anti-HPA-5a alloantibody after platelet transfusion and discuss the clinical
presentation, diagnosis and management of this life threatening condition
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