Nuray Richard
Hepatitis B virus and Hepatitis D virus are two major pathogens responsible for liver diseases, ranging from acute hepatitis to chronic liver conditions, including cirrhosis and hepatocellular carcinoma. HBV, a DNA virus, primarily infects hepatocytes, while HDV, a defective RNA virus, requires HBV for replication. Infected cells are the primary targets for both the adaptive and innate immune responses, but the ability of these viruses to modulate and evade host immune detection complicates their pathogenesis. The interplay between viral infections and the host's immune system is central to disease progression and outcome. This article explores the intrinsic immune responses of HBV/HDV-infected cells, their interactions with innate immune mechanisms, and how this affects the activation of innate immune cells. HBV is a highly infectious virus that primarily infects the liver.
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Virology: Current Research received 187 citations as per Google Scholar report
