Biosensors & Bioelectronics

Electrochemical Studies and Antioxidant Activity of Heterocyclic Nitrate Systems

Abstract

Amlil A, Yassine H, Akhramez S, Touzara S, Ayad H, Elabbadi N, Chtaini A, Hafid A and Khouili M

A nitration by penta-hydrated bismuth (Bi(NO₃)₃.5H₂O) was carried out on two commercial molecules, methoxynaphthalene 1 and naphthalen-2-ol 2. The compounds produced from this organic synthesis (1.a, 1.b, 1.c and 2') as well as the starting molecules 1 and 2 have undergone a study on their antioxidant capacity, using two methods: electrochemical cyclic voltammetry CV and DPPH biologically. The experimental results of the two methods confirm that the antioxidant power of these aromatic molecules is canceled in the case of nitration or by replacement of the hydroxyl group (molecule 2) by the methoxy group (molecule 1).