Hick Jing
Japanese Encephalitis Virus is a flavivirus primarily transmitted to humans through the bite of infected mosquitoes, particularly Culex species. It is the leading cause of viral encephalitis in Asia, with widespread occurrences in countries such as India, China, Thailand, and Vietnam. The virus exists as several genetically distinct strains, with Genotype 4 (G4) emerging as a dominant and highly pathogenic variant in recent years. While JEV primarily affects humans and horses, pigs play a central role in the transmission cycle of the virus, serving as amplifying hosts that allow mosquito vectors to feed on high viral loads. Experimental infections in pigs provide valuable insights into the mechanisms of JEV transmission, pathogenesis, immune responses, and the potential development of vaccines. This article reviews the significance of experimental studies involving JEV Genotype 4 infection in pigs, exploring the findings and their implications for human health and disease control.
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Virology: Current Research received 187 citations as per Google Scholar report
