Canine allergic dermatitis is a common and challenging condition affecting dogs worldwide. This study aimed to investigate the gut microbiota composition in dogs with allergic dermatitis and explore its potential implications for the development of novel therapeutic strategies. Fecal samples were collected from a cohort of dogs diagnosed with allergic dermatitis and healthy controls. High-throughput sequencing of the 16S rRNA gene was employed to analyze the gut microbial communities. Our findings revealed significant alterations in the gut microbiota diversity and composition in dogs with allergic dermatitis compared to healthy controls. Specific bacterial taxa were found to be either enriched or depleted in the diseased group. Moreover, correlation analysis indicated potential associations between certain microbial taxa and clinical parameters of dermatitis severity. These findings suggest a complex interplay between gut microbiota and allergic dermatitis and pave the way for innovative therapeutic interventions targeting the gut-skin axis.
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