The human microbiome, comprising trillions of microorganisms residing in and on the human body, has emerged as a key determinant of human health and disease. In this review, we explore the role of the microbiome in human health and disease using a bioanalytical approach. We discuss the methodologies and techniques employed in microbiome analysis, including high-throughput sequencing, metagenomics, and metabolomics. We highlight the impact of the microbiome on various physiological processes, such as immune system modulation, nutrient metabolism, and drug metabolism. Furthermore, we explore the association between dysbiosis of the microbiome and various diseases, including inflammatory bowel disease, obesity, and autoimmune disorders. We also address the potential of modulating the microbiome as a therapeutic approach. By integrating bioanalytical approaches, we gain a deeper understanding of the complex interactions between the microbiome and human health, paving the way for targeted interventions and personalized medicine.
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Journal of Bioanalysis & Biomedicine received 3099 citations as per Google Scholar report
