Molecular Biomarkers & Diagnosis

Expression of Surface Molecules on Multiple Myeloma Cells and their Potential Role in Pathogenesis, Prognosis, and Treatment

Abstract

K. Kotwica, Maria B.Cioch, Anna Dmoszynska

Multiple myeloma cells express a number of surface molecules capable of activating downstream anti-apoptotic signaling pathways which could favor their growth and survival. Such cell surface molecules have been considered to be prognostic factors for multiple myeloma (MM), as detailed in the following review, and, we speculate, may become possible therapeutic targets in the future.