Journal of Clinical Case Reports

Extensive Solitary 7 × 9 × 11 cm Extracranial and Intracranial Metastasis from Hepatocellular Carcinoma with Orbital Infiltration

Abstract

Hanno M Witte, Sven Duda, Heinrich Weßling, Holger Räkers and Gregor Anzinger

We report the case of a 78-year-old male patient with a solitary 7 cm × 9 cm × 11 cm extracranial and intracranial metastasis from hepatocellular carcinoma. Because of the swelling of his right temporal region, a benign soft-tissue tumor was initially considered as a cause. A resection attempt was performed, resulting in severe bleeding from tumor tissue. A biopsy provided diagnostic evidence of HCC. Eighteen months later the patient presented with a symptomatic secondary generalized seizure and the tumor threatened to ulcerate through the skin. A diagnostic assessment revealed that the tumor extended to the skull base and had infiltrated the orbita, dura, and calvaria.