Nuclear Medicine & Radiation Therapy

Abstract

Bao Zhang

We present a case of a 46-year-old female who was hospitalized with a 20-day history of irregular vaginal bleeding after menopause. Laboratory tests of tumor markers revealed negativity for carcinoma embryonic antigen (CEA) and carbohydrate antigen 125(CA125). Transvaginal ultrasound showed a hypoechoic mass in the cervix uterus. Fluorine-18-Cuorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed a significantly enlarged cervix with an intense metabolic signal due to uptake of 18F-FDG. The patient was negative for systemic FDG metabolism in the lymph nodes and bone marrow. The subsequent histopathologic examination confirmed the diagnosis of primary diffuse large B-Cell lymphoma non-germinal centerB-cell-like (DLBCL-NGCB) of the cervix.