Vitamin D is a multifunctional hormone with diverse physiological roles beyond its classical function in calcium and bone metabolism. Emerging research has highlighted the importance of vitamin D in various biological processes, including immune regulation, cardiovascular health and cancer prevention. This review aims to provide a comprehensive overview of the physiology of vitamin D and its implications for disease prevention. Key topics covered include the mechanisms of vitamin D synthesis, metabolism and signaling pathways, as well as the effects of vitamin D deficiency on health outcomes. Additionally, the potential therapeutic applications of vitamin D supplementation in preventing and managing chronic diseases will be discussed. By enhancing our understanding of the physiological functions of vitamin D, this review seeks to inform healthcare professionals and the general public about the importance of maintaining adequate vitamin D status for optimal health and disease prevention.
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