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Journal of Clinical Neurology and Neurosurgery

ISSN: 2684-6012

Open Access

Gamma-band Changes in Psychiatric Disorders: Understanding the Underlying Pathophysiology

Abstract

Subachhanda Behuriya*

Gamma-band oscillations represent a key feature of neural activity in the brain and play a crucial role in cognitive processes such as perception, attention and memory. Dysregulation of gamma-band activity has been implicated in various psychiatric disorders, including schizophrenia, bipolar disorder, major depressive disorder and anxiety disorders. In this review, we examine the current state of knowledge regarding gamma-band changes in psychiatric disorders, with a focus on understanding the underlying pathophysiology. We discuss the evidence supporting alterations in gamma-band oscillations in different psychiatric conditions, including findings from Electroencephalography (EEG), Magnetoencephalography (MEG) and neuroimaging studies. Furthermore, we explore the potential mechanisms underlying gamma-band dysregulation, including alterations in neurotransmitter systems, synaptic dysfunction and aberrant neural circuitry. By elucidating the role of gamma-band oscillations in psychiatric disorders, this review provides insights into the neurobiological mechanisms underlying these conditions and highlights potential targets for therapeutic intervention.

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