Journal of Genetics and DNA Research

HMG2 and PLAG1 protein expression in Pleomorphic Adenoma Tumorigenesis and its recurrence and in the progression to Carcinoma ex-Pleomorphic Adenoma

Abstract

Louyse CML Vizotto

The Pleomorphic Adenoma (PA) is the most common neoplasm of salivary glands. Recurrences of APs are common and increase the probability of the malignant transformation giving rise to the Carcinoma Ex Pleomorphic Adenoma (CXPA), which, although rare, is an aggressive tumor with frequent metastasis and death related to the disease.