Journal of Tissue Science and Engineering

Human Tissue Engineering: A Relevant Model for Identifying microRNAs Activated by Glioblastoma/Neural Tissue Interaction

Abstract

Erika Cosset

A key challenge in glioblastoma biology and relevant tumor environment modeling lies in understanding of the cellular interactions occuring within the context of a 3-dimensional (3-D) human tissue microenvironment. Recently, human engineered neural tissue raise the opportunity to study such a very important feature of GBM in vitro. Here, we introduce this model for studying microRNAs.