Immunoglobulin A Nephropathy (IgAN), also known as Berger's disease, is the most common primary glomerulonephritis worldwide. It is characterized by the deposition of IgA in the glomeruli, triggering an immune-mediated inflammatory response that leads to renal injury, glomerular inflammation, and ultimately progressive kidney disease. IgAN typically presents with haematuria (blood in the urine), proteinuria (protein in the urine), and can lead to chronic kidney disease (CKD) or even End-Stage Renal Disease (ESRD) in some cases.
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