Hydrophilic nanofibers have emerged as a promising platform for various biomedical applications, including drug delivery systems, wound healing, and tissue engineering. The incorporation of drugs into these nanofibers can significantly influence their physicochemical properties, affecting their performance and efficacy in practical applications. This article reviews the impact of drug incorporation on the properties of hydrophilic nanofibers, including changes in fiber morphology, mechanical strength, hydrophilicity, and drug release profiles. The review highlights the various methods used to incorporate drugs into nanofibers, such as electrospinning and solution blending, and their effects on the nanofiber's characteristics. Furthermore, it discusses the implications of these changes for drug delivery and other biomedical applications. Understanding these impacts is crucial for optimizing nanofiber-based systems for specific therapeutic needs.
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Pharmaceutical Regulatory Affairs: Open Access received 533 citations as per Google Scholar report
