Michael Seong*
Insulin Resistance (IR) is a condition characterized by a reduced response of target tissues to insulin, leading to impaired glucose homeostasis and increased risk of metabolic disorders, including type 2 diabetes mellitus (T2DM), cardiovascular diseases, and Non-Alcoholic Fatty Liver Disease (NAFLD). This review elucidates the multifaceted mechanisms underlying insulin resistance, discusses its clinical implications, and explores current and emerging therapeutic targets. Insulin resistance is a key pathological feature of several metabolic disorders, particularly T2DM. The condition is defined by the body's diminished ability to respond to insulin, which plays a critical role in glucose uptake and metabolism. Understanding the mechanisms of insulin resistance is vital for developing effective treatments and prevention strategies [1].
PDFShare this article
Journal of Diabetic Complications & Medicine received 102 citations as per Google Scholar report