Journal of Computer Science & Systems Biology

Integration of Bioinformatics Tools for Proteomics Research

Abstract

Tushar Nanda, Kadambini Tripathy and Ashwin P

An emerging field for the analysis of biological systems is the study of the complete protein complement of the genome, the ‘proteome’. Proteomics is defined as a scientific approach used to elucidate all protein species within a cell or tissue. Emerging proteomic technologies have promised for early diagnosis and in advancing treatment directions. Application of these technologies has produced new biomarkers, diagnostic approaches, and understanding of disease biology. Here in this review we have outlined potential implications for clinical proteomics focused on applied research activities. This review presents a general survey of the recent development in array technologies from a proteomics perspective. The significance of informatics in proteomics will gradually increase because of the advent of high-throughput methods relying on powerful data analysis. Lastly, an attempt has been made to present novel biological entities named the bioinformatics tools developed to analyse the large protein– protein interaction networks they form, along with several new perspectives of the field. Bioinformatics is an integral part of proteomics research.