Journal of Bioprocessing & Biotechniques

Interpretation and Thinking of the "Precision Medicine Initiative" of the United States

Abstract

Zhao Xiaoyu, Sun Yu, Diao Tianxi, Gao Yunhua, Chen Ting, Kang Di, Wang Lei* and Zeng Yanjun*

Background: On January 20th, 2015, President Obama proposed "Precision Medicine Initiative" in State of the Union address, which lead to close attention and rapid follow-up of many counties around the world, including China. Methods: This paper deeply analyzes the background and motivation of the "precision medical plan" of the United States. On the basis of systematic exposition of the connotation, development history and development conditions of Precision Medicine, the advantages and disadvantages of the development of precision medicine in China are analyzed, and the thinking of the development of precision medicine in China is put forward. Results: Five supporting conditions should be satisfied to ensure the sound development of precision medicine: To establish a new inspiring mechanism for innovations; To establish a new disease classification system incorporating molecular genetic data; To optimize the regulatory system of new drug research; Correct interpretation of genetic data; Encouraging patients to actively participate through appropriate regulations and regulatory measures. Conclusions: During developing the precision medicine research initiative of China, the following factors should be taken into account: focusing on prevention and control of China's major diseases; Closely combining basic medical research with clinical needs; To establish a scientific environment based on big data; To launch research on the making of relevant regulatory policies; Strengthening population-based cohort study.