Molecular Biomarkers & Diagnosis

Intraductal Tubulopapillary Neoplasm: An Unusual Presentation of a Rare Tumor

Abstract

Emmanuel Gabriel, Eisar Al-Sukhni, Moshim Kukar and Steven Hochwald

Intraductal tubulopapillary neoplasm (ITPN) of the pancreas is a relatively new entity with approximately 60 reported cases in the literature. While distinct from mucinous neoplasms of the pancreas, its clinical presentation can be quite varied, thus making this a challenging diagnosis. However, the histopathological characteristics of ITPN are better characterized, lending aid in establishing the diagnosis. In this brief case report, we present an as yet undescribed and unusual presentation of ITPN associated with intratumoral hemorrhage and a high serum lipase level, which normalized following resection.