Journal of Clinical Case Reports

Isolated Intracranial Rosai-Dorfman Disease: A Case Report of F ollow- Up MRI Showing Dynamic Changes of the Lesion

Abstract

Jie Jiang, Dan Han, Yuanming Jiang, Zhenguang Zhang, Fenglin Xue and Bo He*

Rosai-dorfman disease (RDD) is a histiocytic proliferative disorder and considered to be extremely rare in the CNS. In this paper, we reported a patient confirmed as isolated intracranial RDD in a 58-year-old woman. MRI imaging without contrast enhancement two years ago found nothing at the onset of the symptoms. Follow-up CT and MRI imaging one year later showed dynamic changes of the lesion from scratch. This report suggests that the symptoms of RRD are earlier than imaging findings. Moreover, we made a systematic literature review on the disease to better understand it.