Chemical Sciences Journal

Kinetic Investigation of Nitroarylation of Pyrrole with 1-Chloro-4-Nitrobenzene Using a New Multi-Site Phase-Transfer Catalyst under Ultrasonic Condition

Abstract

Selvaraj V, Harikumar K, Sathiyaraj M and Rajendran V

In the present research work, the solid-liquid reaction was successfully carried out in the new synthesized multisite phase-transfer catalyst, namely i.e., 1,3,5-tribenzyl-1,3,5-triethyl-1,3,5-triazinane-1,3,5-triium trichloride(MPTC), and sonication (40 kHz, 300 W) to produce the desired product namely 1-(4-nitropheny) pyrrole from pyrrole and 4-nitrochlorobenzene. The selectivity of N-arylation product was obtained under sonication and MPTC. The combination of ultrasound and MPTC resulted in better efficacy as compared to the individual operations. The apparent reaction rate is greatly enhanced and observed to obey the pseudo-first order kinetics. The kapp value increases with increasing kinetic parameters that is the amount of [MPTC], [substrate], ultrasonication, stirring speed, temperature, etc.