Journal of Clinical Case Reports

Managing Argatroban in Non-Obstructive Thrombosis of Mechanical Mitral Valve in Heparin Induced Thrombocytopenia Type II: A Case Report

Abstract

Bouchot O, Vanzetto G, Casset C and Marlu R

We describe the successful management of argatroban in non-obstructive mechanical heart valve thrombosis in a context of heparin induced thrombocytopenia (HIT) type II. A 77-year-old female with permanent atrial fibrillation and mechanical heart valve developed an asymptomatic non obstructive thrombus of mechanical mitral heart valve diagnosed while she was under argatroban for acute HIT type II. Total disappearance of thrombus was achieved with a medical antithrombotic strategy combining increase of argatroban and VKA dosages and implementation of an antiplatelet treatment with aspirin.