Journal of Clinical & Medical Genomics

Mendelian Inheritance and Clinical Genetics: Translating Basic Research into Clinical Care

Abstract

Karenay Huttan

Mendelian inheritance, the foundational concept in genetics, describes
the inheritance patterns of traits and disorders based on the principles
established by Gregor Mendel in the 19th century. These principles, including
the laws of segregation and independent assortment, laid the groundwork
for understanding how genetic traits are passed down through generations.
In clinical genetics, Mendelian inheritance plays a pivotal role in diagnosing
and managing hereditary conditions, providing insights into the genetic
underpinnings of diseases that follow simple inheritance patterns.