Journal of Clinical Case Reports

Metastatic Ameloblastoma to the Liver: Rare Presentation of a Rare Disease

Abstract

Lacin S, Dogrul A, Dikmen E, Kertmen N, Turker A and Kars A

Ameloblastoma is a slow growing odontogenic epithelial neoplasm which originates from remnants of the dental lamina with a high recurrence rate, but a low tendency to metastasize. Locally invasive ameloblastoma is often aggressive and destructive, which erodes bone and invades adjacent structures. Despite a benign histology metastatic disease may occur and samples taken from metastatic tumor usually maintains the features of the original tumor. Ameloblastic carcinoma differs from ameloblastoma with malignant cytological features. Here we report an unusual case of ameloblastoma metastatic to lung and liver, unresponsive to systemic treatment with cisplatin and adriamycin, and well controlled with local surgical treatment.