Journal of Clinical Case Reports

Miller Fisher Syndrome Variant: The Incomplete Triad

Abstract

Noorhayati Binti Mohamad Nadzir, Puspha Raman*, Premala Devi S and Khairul Husnaini Mohd Khalid

Miller Fisher Syndrome (MFS) is a rare inflammatory peripheral neuropathy where the diagnosis is made based on the clinical triad of ophthalmoplegia, ataxia, and areflexia. It is considered a variant of Guillain-Barré Syndrome (GBS) and associated with antiGQ1b IgG positive serology. Reports on cerebellar ataxia and supranuclear gaze palsy in MFS suggested an additional involvement of the central nervous system, encompassing Bickerstaff's Brainstem Encephalitis (BBE) spectrum.