Journal of Bioprocessing & Biotechniques

Multifunctional Magnetic Bead-Based Dynamic Light Scattering Aptasensor with Rapid and Feasible Determination of Disease-Related Biomarkers

Abstract

Ying Tang, Jin Zhang and Dianping Tang

A simple and feasible sensing strategy based on target-induced aggregation of aptasensor-conjugated multifunctional magnetic beads was designed for sensitive detection of low-abundant proteins (carcinoembryonic antigen, CEA, used as an example), coupling with dynamic light scattering technique.