Phytochemicals, also known as secondary metabolites, are plant-produced substances that have been shown to have a wide range of biological activities, providing a scientific basis for the use of herbs in traditional medicine.Furthermore, the use of herbs is thought to be safer and less expensive than synthetic medicine.Herbal medicines, on the other hand, have drawbacks such as low solubility, stability, and bioavailability. Some of them can degrade physically and chemically, reducing their pharmacological activity. Nanotechnology-based herbal drug formulations have attracted attention in recent decades due to their increased activity and potential for overcoming the problems associated with herbal medicine. Approaches that use biocompatible, biodegradable nanotechnology-based delivery systems based on lipids, polymers, or nanoemulsions can improve the solubility, stability, bioavailability, and pharmacological activity of herbals.The purpose of this review article is to provide an overview of the most recent advances in the development of nanotechnology-based herbal drug formulations for increased activity, as well as a summary of the challenges that these herbal medicine delivery systems face.
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