Journal of Bioanalysis & Biomedicine

Nobel Metallic Nanoparticles with Novel Biomedical Properties

Abstract

F Stanley Rosarin and S Mirunalini

The strong optical absorption and scattering of noble metal nanoparticles is due to an effect called localized Surface Plasmon Resonance, which enables the development of novel biomedical applications. AuNPs are the most stable metal nanoparticles, and they present fascinating aspects such as their assembly of multiple types involving materials science, the behavior of the individual particles, size-related electronic, magnetic and optical properties [quantum size effect], and their applications to catalysis and biology likewise, AgNPs due to its excellent biocompatibility and antibacterial property raise considerable interest as nanoparticles for biomedical applications. Since the size, shape and composition of silver nanoparticles can have significant effect on their efficacy, extensive research has gone into synthesizing and characterizing silver nanoparticles. This article reviews the various synthetic routes currently used for developing stable silver nanoparticles and their biomedical applications in the areas of microbial resistance, antioxidant activity, anticancerous, drug delivery, antiplatlet, antiangiogenic activity, surface enhanced Raman scattering and metal enhanced fluorescence.