Journal of Bioengineering & Biomedical Science

Pharmacognostic, Phytochemical and Pharmacological Studies of Cassia roxburghii

Abstract

Pallavi Kamarapu

In the present study, the leaf of Cassia roxburghii and its powder were subjected to pharmacognostic evaluation in terms of macroscopic and microscopic evaluation. The powdered drug was subjected to extraction with various solvents such as petroleum ether, chloroform, ethyl acetate, methanol and aqueous extract by successive maceration. The methanolic and aqueous leaf extracts exhibited reducing power compared with ascorbic acid at similar concentrations. Based on the biochemical estimation of serum marker enzymes and histological study, all the extracts showed hepato protective activity and the maximum activity was seen in methanol extract at 200 mg/kg. The order of activity Me200>aq200>Me400>Aq400.