Journal of Tissue Science and Engineering

Prevention of Adhesions by PL/PG after Adhesiolysis

Abstract

Akerberg D, Posaric Bauden M, Isaksson K, Andersson R and Tingstedt B

Background: Previous studies of differently charged polypeptides, Poly-L-lysine (PL) and Poly-L-Glutamate
(PG) have shown promising results, reducing postoperative adhesions. This study aimed to investigate the possible anti adhesion effect of those combined polypeptides, after adhesiolys. The concentration of tPA, PAI-1 and active TGFb1 in biopsies from adhesions, unharmed peritoneum before and after adhesiolysis, was also investigated.