Journal of Cytology & Histology

Primary CNS Lymphoma- a Squash Diagnosis

Abstract

Pallavi Bhuyan, Pranati Mohanty, Kaumudi Pattnaik, Aparajita Mishra, Priya Biswal and Jayasree Rath

Primary CNS Lymphoma (PCNSL) is a rare form of extranodal non-Hodgkin's lymphoma. It has a varied presentation and cytomorphology. We diagnosed a case of PCNSL in a 52-year old male in intra-operative squash cytosmear differentiating from other lesions. In cytosmear even gradient of cellular density, monomorphic tumour cells with lack of cellular cohesion on a background showing good no. of tingible body macrophages and lymphoglandular bodies were the characteristic features. Histomorphology showed the features of diffuse large cell lymphoma and was immunohistochemically confirmed as B-cell type (DLBCL).